Key Step in Cosmetic Products Development
In vitro tests play a fundamental role in developing a cosmetic. The term in vitro (Latin for “in glass”) is used to denote studies of biological process under artificial conditions, outside the living organism. Accordingly, tests of cosmetic materials and final products are performed on isolated skin cells.
In vitro tests are able to assess the impact of cosmetic materials and finished product using cells and reconstructed tissues. Therefore, the toxicological potential of cosmetic raw material and finished products can be evaluated using these non-animal models. They may also help in discriminating the effects of each cosmetic component.
Skin cells in in vitro cultures are used to assess impact of stress factors (e.g. UV or free radicals) on cells structure. In vitro tests include studies of cosmetics materials’ cytotoxicity, evaluation of the level of synthesis and cell activity of enzymatic proteins, effects of growth agents and various types of compounds ultimately influencing the skin aging processes
- Ecotoxicology / Biodegradability
- In-vitro safety studies